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Text File  |  1987-10-07  |  458b  |  14 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, CLONIDINE DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (EXCESSIVE SEDATION).
  4.  
  5.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE ADJUSTED
  6.          BASED ON THE PATIENT'S CREATININE CLEARANCE:
  7.  
  8.                      CREATININE
  9.                       CLEARANCE            DOSAGE
  10.                      (ML/MINUTE)
  11.  
  12.                         <10          50 to 75% of normal
  13.  
  14.